Benoquin cream contains monobenzone as active ingredient. Benoquin cream is also known as monobenzone cream. This medication works by increasing elimination of melanin from skin cells. It is used to permanently lighten skin in people with vitiligo. De pigmenting darker skin around the areas of vitiligo helps even out coloring and appearance of the skin. Monobenzone is not used to treat freckles, sun damage, jaundice, café-au-lait spots, melanoma or other pigmentation disorder not caused by vitiligo. Monobenzone is a de pigmenting agent.